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肝癌TACE的随访

时间:2022-02-23 00:42来源:www.ynjr.net 作者:杨宁介入医学网
TACE术后病人的随访包括临床和影像 BCLC staging and treatment strategy, 2012 Forner, et al. Lancet. 2012 Mar 31;379(9822):1245-55. 为什么说TACE是中期肝癌的标准治疗 *P values refer to cumulative meta-analysis of five and six studies, respecti

TACE术后病人的随访包括临床和影像



BCLC staging and treatment strategy, 2012
Forner, et al. Lancet. 2012 Mar 31;379(9822):1245-55.



为什么说TACE是中期肝癌的标准治疗
*P values refer to cumulative meta-analysis of five and six studies, respectively.
BCLC, Barcelona Clinic Liver Cancer; GRETCH, Groupe d'Etude et de Traitement du Carcinome Hépatocellulaire; HCC,
hepatocellular carcinoma; TACE, transarterial chemoembolization

Llovet JM et al. Hepatology 2003;37:429–42.

TACE术后结果不好的预后因素包括


病人特征 肿瘤特征 技术相关
1.  Child-Pugh B【1–9】
2.  Alpha-fetoprotein
(≥400 ng/mL)【2,6,8,9】
3. Grade 3 ascites【5,10,11】
4. Bilirubin >3 mg/dL【2,7,8】
5. Performance status >1【3,12】
1. >3 liver lesions【1-3】
2. Tumor diameter ≥ 5cm【4-7】
3. Multi-nodular/diffuse
tumour【1,5,8】
4. Bilobar tumour【1,3】
5. Portal vein thrombosis【1,9】
1. Non-selective TACE
procedures (lobar/bilobar)【 1-3】
.2.  Conventional TACE【4-6】
1. Dumortier J, et al. Dig Liver Dis 2006;38:125–33
 
2. Savastano S, et al. J Clin Gastroenterol 1999;28:334–40; 

3. Doffoël M, et al. Eur J Cancer 2008;44:528–38; 
 
4. Florio F, et al. Cardiovasc Intervent Radiol 1997;20:23–8; 

5. Pietrosi G, et al. J Vasc Intervent Radiol 2009;20:896-902; 

6. Yip WM, et al. Hong Kong Med J 2009;15:339-45;

7. Gomes AS, et al. AJR Am J Roentgenol 2009;193:1665-71; 

8. Mabed et al. Eur J Cancer Care 2009;18:492-9; 

9. Forner et al. Seminars Liver Dis 2010;30:61-74; 

10. Cho YK, Cancer 2008;112:352-61; 

11. Lladó L, et al. Cancer 2000;88:50–7; 

12
1. Lladó L, et al. Cancer 2000;88:50–7;

2. Mabed et al. Eur J Cancer Care 2009;18:492-9;

3. Vogl TJ, et al. Radiol 2000;214:349-57;

4. Sotiropoulos GC, et al. Dig
Dis Sci 2009;54:2264-73;

5. Dumortier J, et al. Dig Liver
Dis 2006;38:125–33;

6. Savastano S, et al. J Clin
Gastroenterol 1999; 28:334–40;

7. Doffoël M, et al. Eur J
Cancer 2008; 44:528–38;

8. Lopez RR, et al. Arch Surg
2002; 137:653–658;

9. Sart K, et al. Cancer
1993;72:3202–9.
1. Cammà C, et al. Radiology 2002;224:47–54;
 
2. Yip WM, et al. Hong Kong Med J 2009;15:339-45; 3.
 
Kothary N, et al. J Vasc Interv Radiol 2007;18:1517–26;
 
4. Lammer J, et al. Cardiovasc Intervent Radiol 2010; 33:4152.

5. Malagari K et al. Cardiovasc Intervent
Radiol 2010; 33:541-51.

6. Varela M et al. J Hepatol
2007;46:474–81. 
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