名词和定义历史 淋巴解剖 淋巴生理 淋巴相关疾病 淋巴影像 淋巴介入 淋巴介入疗效 淋巴介入并发症
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淋巴介入治疗的历史

时间:2020-09-30 23:50来源:未知 作者:Mr.Editor
Jean Pecquet (1622-1674) describes Thoracic duct in dogs (1651) Olaf Rudbeck (1630-1702) describes human lymphatic system (1653) Frederick Ruysch (1638-1731) describes valves in lymph vessels (1712)


Jean Pecquet (1622-1674) describes Thoracic duct in dogs (1651)


Olaf Rudbeck (1630-1702) describes human lymphatic system (1653)


Frederick Ruysch (1638-1731) describes valves in lymph vessels (1712)

Liver Lymphatic System 肝淋巴系统



  • First described liver lymphatic flow 首次阐述肝淋巴引流
  • Normal liver lymph contributes 30-40% of the  flow to the TD(胸导管)
  • Estimate 500-800 ml/day
  • 40% of total body proteins returned to blood  circulation through TD
 

Ernest Starling (1894)  


 History of Lipiodollymphography
  • 1954 : Kinmonth (US) : pedal denudation (patent blue violet) of lymphatic duct –hydrophylic iodinated solutions
  • 1960 : Wallace (US) : oily iodinated contrast medium (Lipiodol)
  • 1960 : Balmes (France) : “magnificent radiographic images”
 
 

  • Kinmonth (1952)
              Introduced subcutaneous injection of patent blue
  • 1960 (Rüttiman, Wallace, Picard et al.)
               Introduction of Lipiodol
  • 1960-1985 “The” lymph node modality
  • > 1985
               Quick / complete disappearance after introduction  CT
 

 



Lymphography -history

  • Excellent technique imaging lymphatic  system -pre CT era 前CT时代最好的淋巴系统影像技术
  • Dx and Tx lymphatic circulation disorders 诊断和治疗淋巴循环疾病
  • Lymphoma and GU malignancies 淋巴瘤和泌尿生殖系肿瘤
  • Pedal lymphography 经足背淋巴造影术
  • Nodal lymphography 淋巴结造影术

     

Central lymphatic flow physiology was extensively studied in up to the 1970’s.
 
     在20世纪70年代,中央淋巴流动生理学曾被广泛研究。
 
然后,有关淋巴系统的研究
 
     50 years of Hiatus! [haɪˈeɪtəs] 沉寂50年 
 
理由很简单

   • Absence of lymphatic imaging methods 缺乏淋巴影像方法
   • Absence of interventional techniques 缺少淋巴介入技术

Major obstacles['ɒbstəklz]障碍
▪ Complex and variable anatomy
▪ Small size of the lymphatic vessels
▪ Difficulty in introduction of the contrast

搅皱无波古井的人是Constantine Cope(1927-2016),法国出生的美国医生

Lymphatic Imaging 由于 

1. Dynamic contrast enhanced MR lymphangiography
2. Intranodal lymphangiography

进入一个新的时代

Constantine Cope (1927-2016) first described minimally invasive 
lymphatic intervention

第一个把导管送进胸导管进行栓塞的人

Cope C. Percutaneous thoracic duct cannulation: feasibility study in swine. J Vasc Interv Radiol.1995;6:559–564.

New Age of Lymphatic Imaging and Interventions
淋巴影像与介入的新时代


淋巴影像与介入的复兴:
REBIRTH OF LYMPHATIC INTERVENTIONS
 
Old Knowledge
New Technology


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